Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787922 | 0.84 | DRD2 (0.50) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL7604476 | 0.84 | NOTUM (0.52) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8788607 | 0.84 | DRD2 (0.50) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL7608385 | 0.84 | NOTUM (0.52) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL7609591 | 0.84 | NOTUM (0.52) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL14301512 | 0.82 | ROCK2 (0.53) | DRD2DRD3KCNH2MCHR1ROCK2 | |
| SCHEMBL9273396 | 0.82 | NOTUM (0.59) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8788725 | 0.81 | CA12 (0.57) | DRD2DRD3NOTUM | |
| SCHEMBL6507548 | 0.81 | ROCK2 (0.53) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL7604788 | 0.81 | ROCK2 (0.53) | DRD2DRD3KCNH2NOTUMMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| CN-1203599-A | Substitued pyrrolidinone, thiazolidinone or oxazolidinone as herbicides | ZENECA LTD (GB) | 1998-12-30 | — | — | CN | disclosed |
| EP-0863894-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| WO-1997020838-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-06-12 | — | — | WO | disclosed |