Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552157 | 0.82 | DRD2 (0.44) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL6508550 | 0.82 | CA12 (0.43) | DRD2DRD3 | |
| SCHEMBL8089666 | 0.82 | DRD2 (0.44) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8103660 | 0.82 | NOTUM (0.45) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8662424 | 0.80 | MCHR1 (0.39) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8662419 | 0.80 | MCHR1 (0.39) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL6508393 | 0.79 | TRPA1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL27509180 | 0.79 | GCGR (0.39) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL7608380 | 0.78 | ROCK2 (0.53) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL7604788 | 0.78 | ROCK2 (0.53) | DRD2DRD3KCNH2OPRL1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000824-A1 | LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |