Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553617 | 0.88 | HDAC4 (0.32) | HDAC4S1PR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL8552608 | 0.88 | L3MBTL1 (0.35) | S1PR1L3MBTL1NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8552750 | 0.85 | NR1I2 (0.46) | HDAC4NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8555392 | 0.75 | L3MBTL1 (0.35) | S1PR1L3MBTL1NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8551725 | 0.74 | — | — | |
| SCHEMBL8554365 | 0.73 | NR1I2 (0.46) | HDAC4NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8558789 | 0.71 | HDAC4 (0.35) | HDAC4S1PR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL8687152 | 0.69 | HDAC4 (0.34) | HDAC4 | |
| SCHEMBL9087925 | 0.67 | NR1I2 (0.45) | HDAC4S1PR1NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8602514 | 0.66 | HDAC4 (0.41) | HDAC4S1PR1TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |