Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554365 | 0.88 | NR1I2 (0.46) | NR1I2CYP3A4CYP2D6HDAC4HDAC6 | |
| SCHEMBL8552608 | 0.87 | L3MBTL1 (0.35) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8552164 | 0.85 | HDAC4 (0.32) | NR1I2CYP3A4CYP2D6HDAC4 | |
| SCHEMBL8555392 | 0.74 | L3MBTL1 (0.35) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8551725 | 0.73 | — | — | |
| SCHEMBL8553617 | 0.73 | HDAC4 (0.32) | NR1I2CYP3A4CYP2D6HDAC4 | |
| SCHEMBL8665008 | 0.68 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6HDAC4HDAC6 | |
| SCHEMBL9117253 | 0.68 | NR1I2 (0.59) | NR1I2CYP3A4CYP2D6HDAC4HDAC6 | |
| SCHEMBL8666605 | 0.67 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6HDAC4HDAC6 | |
| SCHEMBL16085836 | 0.67 | NR1I2 (0.68) | NR1I2CYP3A4CYP2D6HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |