Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552164 | 0.88 | HDAC4 (0.32) | L3MBTL1S1PR1NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8555392 | 0.87 | L3MBTL1 (0.35) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8552750 | 0.87 | NR1I2 (0.46) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8551725 | 0.77 | — | — | |
| SCHEMBL8670644 | 0.76 | L3MBTL1 (0.43) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8553617 | 0.75 | HDAC4 (0.32) | L3MBTL1S1PR1NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8554365 | 0.74 | NR1I2 (0.46) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL16086028 | 0.63 | CYP3A4 (0.46) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8666649 | 0.63 | CYP3A4 (0.46) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL18471229 | 0.63 | L3MBTL1 (0.60) | L3MBTL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |