Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552089 | 0.92 | HTR1F (0.52) | HTR1FL3MBTL1NPC1RAB9ATDP1 | |
| SCHEMBL8709033 | 0.90 | HTR1F (0.48) | HTR1FL3MBTL1NPC1RAB9ATDP1 | |
| SCHEMBL8552580 | 0.87 | HTR1F (0.65) | HTR1FNPC1RAB9ATDP1SNCA | |
| SCHEMBL8549838 | 0.81 | ALDH1A1 (0.47) | HTR1FNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6647888 | 0.80 | HTR1F (0.75) | HTR1FL3MBTL1NPC1RAB9ATDP1 | |
| SCHEMBL7142148 | 0.80 | HTR1F (0.76) | HTR1FL3MBTL1SNCAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7139630 | 0.79 | HTR1F (0.75) | HTR1FL3MBTL1SNCAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8552477 | 0.79 | NPC1 (0.39) | HTR1FL3MBTL1NPC1RAB9ATDP1 | |
| SCHEMBL8549636 | 0.78 | HTR1F (0.51) | HTR1FL3MBTL1RAB9ATDP1ALDH1A1 | |
| SCHEMBL8547488 | 0.78 | HTR1F (0.53) | HTR1FL3MBTL1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |