Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.70 |
| ▸ | HTR6 | P50406 | 8/20 | 0.68 |
| ▸ | DRD2 | P14416 | 5/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.63 |
| ▸ | SCN1A | P35498 | 2/20 | 0.61 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.61 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.61 |
| ▸ | CCR1 | P32246 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111481 | 0.95 | HTR7 (0.66) | HTR7HTR6DRD2HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL11101388 | 0.90 | SLC6A9 (0.63) | HTR7HTR6DRD2HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL11101542 | 0.88 | ALOX15 (0.64) | HTR7HTR6DRD2HTR2AHTR1A | |
| SCHEMBL7322195 | 0.85 | PRKD3 (0.60) | HTR7HTR6DRD2HTR2AHTR1A | |
| SCHEMBL11101165 | 0.85 | HTR7 (0.67) | HTR7HTR6DRD2HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL11111993 | 0.84 | HTR7 (0.67) | HTR7HTR6DRD2HTR2AHTR1A | |
| SCHEMBL8979733 | 0.82 | HTR7 (1.00) | HTR7HTR6DRD2HTR2AHTR1A | |
| SCHEMBL10978527 | 0.82 | PRKD3 (0.62) | HTR7HTR6DRD2HTR2AHTR1A | |
| SCHEMBL24069062 | 0.82 | HTR7 (0.68) | HTR7HTR6DRD2HTR2AHTR1A | |
| SCHEMBL8982867 | 0.82 | HTR7 (0.98) | HTR7HTR6DRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883613-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-12-16 | — | — | EP | claimed |
| WO-1997029097-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-14 | — | — | WO | claimed |