Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300761 | 0.82 | SNCA (0.42) | ALDH1A1CYP3A4CA1CA2MEN1 | |
| SCHEMBL8552652 | 0.82 | HTT (0.52) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| Allyl Alcohol SCHEMBL8437400 | 0.80 | SNCA (0.40) | ALDH1A1CYP3A4CA1CA2MEN1 | |
| SCHEMBL8441196 | 0.78 | NPSR1 (0.35) | CYP3A4CA1CA2MEN1KMT2A | |
| SCHEMBL11497029 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4LMNAMEN1 | |
| SCHEMBL17513682 | 0.72 | CYP3A4 (0.58) | ALDH1A1MAPTCYP3A4LMNAMEN1 | |
| SCHEMBL6215267 | 0.72 | CYP3A4 (0.47) | ALDH1A1MAPTCYP3A4LMNAGAA | |
| SCHEMBL4677464 | 0.72 | CYP3A4 (0.47) | ALDH1A1MAPTCYP3A4LMNAGAA | |
| SCHEMBL8102643 | 0.71 | TSHR (0.37) | ALDH1A1CYP3A4CA1CA2MEN1 | |
| SCHEMBL8104182 | 0.68 | TSHR (0.44) | ALDH1A1CYP3A4CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997002242-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-01-23 | — | — | WO | disclosed |