Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853528 | 0.79 | MAPT (0.43) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL20718828 | 0.79 | MAPT (0.43) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL28304724 | 0.79 | KMT2A (0.51) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL12726296 | 0.76 | MAPT (0.49) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL28305788 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL22165764 | 0.74 | MAPT (0.49) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL20718858 | 0.74 | NPC1 (0.42) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL1641895 | 0.74 | MAPT (0.47) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8552393 | 0.74 | MAPT (0.46) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL2062103 | 0.73 | SMN1; SMN2 (0.64) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |