Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234539 | 0.82 | TSHR (0.43) | MMP8PRKCAMEN1KMT2ATSHR | |
| SCHEMBL234014 | 0.82 | MMP8 (0.56) | MMP8MEN1KMT2ATSHR | |
| SCHEMBL235598 | 0.78 | MMP8 (0.41) | MMP8 | |
| SCHEMBL235100 | 0.78 | MMP8 (0.41) | MMP8MEN1KMT2ATSHR | |
| SCHEMBL27724022 | 0.77 | MMP8 (0.51) | MMP8MEN1KMT2ATSHR | |
| SCHEMBL234361 | 0.76 | MMP8 (0.41) | MMP8TSHR | |
| SCHEMBL235847 | 0.75 | ALDH1A1 (0.47) | MMP8TSHR | |
| SCHEMBL236285 | 0.74 | TSHR (0.40) | MMP8MEN1KMT2ATSHR | |
| SCHEMBL9052824 | 0.74 | MMP8 (0.53) | MMP8MEN1KMT2ATSHR | |
| SCHEMBL28553368 | 0.74 | NAAA (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932747-A | Method for preparing 1,3-dioxane compounds | HUELS AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | claimed |