Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553781 | 0.81 | SLC6A4 (0.43) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL8814238 | 0.80 | SMN1; SMN2 (0.37) | GAADDB1CRBNMEN1KMT2A | |
| SCHEMBL7360048 | 0.80 | ALOX5 (0.50) | GAADDB1CRBNBRD4CREBBP | |
| SCHEMBL8442975 | 0.73 | CRBN (0.55) | GAAKDM4ETSHRMAP2K1DDB1 | |
| SCHEMBL20041851 | 0.72 | KDM1A (0.47) | GAAKDM4ETSHRMAP2K1DDB1 | |
| SCHEMBL19559429 | 0.72 | KDM1A (0.47) | GAAKDM4ETSHRMAP2K1DDB1 | |
| SCHEMBL20041901 | 0.72 | KDM1A (0.47) | GAAKDM4ETSHRMAP2K1DDB1 | |
| SCHEMBL6827562 | 0.70 | DDB1 (0.51) | GAAKDM4ETSHRMAP2K1DDB1 | |
| SCHEMBL6686171 | 0.70 | BRD4 (0.50) | KDM4ETSHRBRD4CREBBPRAB9A | |
| SCHEMBL17276246 | 0.70 | GAA (0.40) | GAAKDM4ETSHRMAP2K1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997002242-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-01-23 | — | — | WO | disclosed |