Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477349 | 1.00 | MEN1 (0.36) | MEN1KMT2ALRRK2CTSSS1PR4 | |
| SCHEMBL8480353 | 0.87 | AAK1 (0.39) | CTSSS1PR4ALPLALDH1A1AAK1 | |
| SCHEMBL7774645 | 0.82 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1GAARAB9A | |
| SCHEMBL7773936 | 0.82 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1GAARAB9A | |
| SCHEMBL8551128 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1GAARAB9A | |
| SCHEMBL7770375 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1GAARAB9A | |
| SCHEMBL7774215 | 0.76 | GRM2 (0.34) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2146575 | 0.75 | CTSS (0.49) | MEN1KMT2ALRRK2CTSSS1PR4 | |
| SCHEMBL7766496 | 0.73 | MEN1 (0.39) | MEN1KMT2AALDH1A1NOTUMRAB9A | |
| SCHEMBL7771575 | 0.73 | MEN1 (0.39) | MEN1KMT2AALDH1A1NOTUMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |