Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554425 | 0.91 | SCN8A (0.43) | SCN8AMRGPRX4MAPTGRM5ABCC3 | |
| SCHEMBL28412531 | 0.81 | HTR1A (0.41) | SCN8AMRGPRX4MAPTTTRALB | |
| SCHEMBL8137092 | 0.81 | SCN8A (0.41) | SCN8AMAPTCYP1A2CYP2D6KMT2A | |
| SCHEMBL347967 | 0.79 | KDM4E (0.46) | SCN8AMAPTESR1CYP1A2CYP2D6 | |
| SCHEMBL13480569 | 0.79 | GPR35 (0.41) | SCN8AMAPTGRM5CYP1A2CYP3A4 | |
| SCHEMBL9523339 | 0.78 | SCN8A (0.39) | SCN8AMAPTCYP1A2CYP2D6KMT2A | |
| SCHEMBL8876567 | 0.78 | SCN8A (0.39) | SCN8AMAPTCYP1A2CYP2D6KMT2A | |
| SCHEMBL72030 | 0.78 | KMT2A (0.46) | MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL5314384 | 0.78 | FFAR4 (0.36) | EGLN2 | |
| SCHEMBL24942168 | 0.77 | KDM4E (0.49) | SCN8ACYP1A2CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |