Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 9/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523339 | 1.00 | SCN8A (0.39) | SCN8AMAOBMAOAMAPTMEN1 | |
| SCHEMBL8137092 | 0.94 | SCN8A (0.41) | SCN8AMAOBMAOAMAPTMEN1 | |
| SCHEMBL30123599 | 0.81 | SCN8A (0.41) | SCN8AMAPTMEN1KMT2ATHRA | |
| SCHEMBL13623362 | 0.80 | ALDH1A1 (0.35) | SCN8AMAOBMAOAMAPTMEN1 | |
| SCHEMBL8552558 | 0.78 | SCN8A (0.40) | SCN8AMAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8554425 | 0.77 | SCN8A (0.43) | SCN8AMAPTMEN1KMT2ATHRA | |
| SCHEMBL28412531 | 0.75 | HTR1A (0.41) | SCN8AMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24942168 | 0.74 | KDM4E (0.49) | SCN8AMEN1KMT2ATHRATHRB | |
| SCHEMBL9520675 | 0.74 | MAOB (0.36) | SCN8AMAOBMAOAMAPT | |
| SCHEMBL8138042 | 0.73 | THRA (0.38) | MAOBMAOAMEN1KMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |