Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480747 | 0.83 | ESR1 (0.43) | S1PR1GAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27302024 | 0.81 | CHRM2 (0.41) | S1PR1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL8315658 | 0.80 | ALOX15 (0.43) | S1PR1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8316603 | 0.79 | ALOX15 (0.42) | S1PR1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL5800338 | 0.77 | CYP26A1 (0.37) | RAB9ANPC1POLBGAAMAPT | |
| SCHEMBL8311891 | 0.76 | S1PR1 (0.39) | S1PR1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL8315798 | 0.75 | S1PR1 (0.38) | S1PR1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL8311404 | 0.73 | ESR1 (0.48) | RAB9ANPC1POLBGAAKDM4E | |
| SCHEMBL6598943 | 0.71 | CYP2C8 (0.37) | S1PR1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6597050 | 0.70 | RAB9A (0.37) | RAB9ANPC1POLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |