Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516744 | 0.78 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL17073100 | 0.78 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL8549295 | 0.75 | MEN1 (0.64) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL8551720 | 0.75 | SIGMAR1 (0.60) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| Hydrochloric Acid SCHEMBL8553181 | 0.74 | SIGMAR1 (0.59) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| Hydrochloric Acid SCHEMBL8686857 | 0.74 | MEN1 (0.62) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL8552616 | 0.74 | BCHE (0.48) | MEN1KMT2ABCHEMAPTPOLB | |
| SCHEMBL6250773 | 0.72 | SLC6A2 (0.55) | MEN1KMT2APOLBMAOBMAOA | |
| SCHEMBL23407877 | 0.72 | KMT2A (0.48) | MEN1KMT2APOLB | |
| SCHEMBL5215671 | 0.72 | CES2 (0.57) | MEN1KMT2AMAPTPOLBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |