Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.62 |
| ▸ | RXRA | P19793 | 6/20 | 0.48 |
| ▸ | RXRB | P28702 | 5/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | ATR | Q13535 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555990 | 0.87 | NR4A2 (0.62) | NR4A2RXRARXRBRXRGPTGS2 | |
| SCHEMBL8547182 | 0.81 | NR4A2 (0.50) | NR4A2RXRARXRBRXRGATR | |
| SCHEMBL7505639 | 0.80 | NR4A2 (0.73) | NR4A2RXRARXRBRXRGPTGS2 | |
| SCHEMBL7509020 | 0.80 | NR4A2 (0.73) | NR4A2RXRARXRBRXRGPTGS2 | |
| Methane SCHEMBL6315958 | 0.79 | PTGS2 (0.54) | NR4A2RXRARXRBRXRGATR | |
| Methane SCHEMBL6315345 | 0.79 | USP1 (0.47) | NR4A2RXRARXRBRXRGATR | |
| Methane SCHEMBL6743761 | 0.79 | USP1 (0.47) | NR4A2RXRARXRBRXRGATR | |
| SCHEMBL5098755 | 0.78 | NR4A2 (1.00) | NR4A2RXRARXRBRXRGPTGS2 | |
| SCHEMBL8556511 | 0.77 | NR4A2 (0.46) | NR4A2RXRARXRBRXRGATR | |
| SCHEMBL6309673 | 0.77 | NR4A2 (0.59) | NR4A2RXRARXRBRXRGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |