Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553278 | 0.81 | TSHR (0.52) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7352542 | 0.76 | TSHR (0.56) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18740215 | 0.75 | MAPK1 (0.40) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8552268 | 0.74 | TSHR (0.55) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2200208 | 0.73 | TSHR (0.54) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8553077 | 0.73 | TSHR (0.42) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1229958 | 0.72 | PKM (0.44) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18740310 | 0.72 | MAPK1 (0.54) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL7302490 | 0.72 | TSHR (0.59) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8552869 | 0.72 | TSHR (0.52) | TSHRALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |