Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 5/20 | 0.33 |
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553294 | 0.88 | S1PR4 (0.33) | — | |
| SCHEMBL8550147 | 0.87 | — | — | |
| SCHEMBL8547164 | 0.87 | TDP1 (0.38) | TDP1METALDH1A1HSP90AA1PIK3CD | |
| SCHEMBL8552372 | 0.86 | PTGS2 (0.36) | ALDH1A1MAPT | |
| SCHEMBL8672349 | 0.85 | TLR8 (0.39) | TDP1METALDH1A1HSP90AA1PIK3CD | |
| SCHEMBL8548819 | 0.84 | TDP1 (0.35) | TDP1METBRD4PIK3CDPIK3CA | |
| SCHEMBL8552700 | 0.79 | TDP1 (0.39) | TDP1METBRD4MAPTRPS6KA5 | |
| SCHEMBL8551852 | 0.76 | NCF1 (0.33) | METCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL8548824 | 0.74 | TDP1 (0.35) | TDP1METBRD4RPS6KA5 | |
| SCHEMBL8553963 | 0.74 | TDP1 (0.35) | TDP1METBRD4RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |