Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547164 | 0.89 | TDP1 (0.38) | NCF1RXRAPPARGNR1H3MAPT | |
| SCHEMBL8551375 | 0.88 | KDM4E (0.39) | NCF1MEN1POLBKMT2AMAPT | |
| SCHEMBL8550780 | 0.88 | RXRA (0.37) | NCF1RXRAPPARGNR1H3POLB | |
| SCHEMBL8553294 | 0.77 | S1PR4 (0.33) | — | |
| SCHEMBL8672349 | 0.77 | TLR8 (0.39) | MEN1KMT2ALMNASMN1; SMN2MET | |
| SCHEMBL8551858 | 0.76 | NCF1 (0.34) | NCF1RXRAPPARGNR1H3MEN1 | |
| SCHEMBL8667811 | 0.75 | CACNA1D (0.36) | MEN1KMT2AKDM4E | |
| SCHEMBL8550147 | 0.75 | — | — | |
| SCHEMBL8668966 | 0.75 | SMN1; SMN2 (0.38) | CYP2C9KMT2AMAPTLMNAKDM4E | |
| SCHEMBL8672721 | 0.74 | PTGS2 (0.40) | MEN1POLBKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |