Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554371 | 0.91 | NR1I2 (0.49) | NR1I2CYP3A4CYP2D6HDAC6HDAC4 | |
| SCHEMBL8552618 | 0.86 | L3MBTL1 (0.37) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8552168 | 0.83 | HDAC4 (0.37) | NR1I2CYP3A4CYP2D6HDAC4 | |
| SCHEMBL8661872 | 0.78 | NR1I2 (0.51) | NR1I2CYP3A4CYP2D6HDAC6HDAC1 | |
| SCHEMBL8555395 | 0.76 | L3MBTL1 (0.36) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8553627 | 0.74 | HDAC4 (0.35) | NR1I2CYP3A4CYP2D6HDAC4 | |
| SCHEMBL8551731 | 0.73 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL8662288 | 0.73 | HDAC6 (0.48) | NR1I2CYP3A4CYP2D6HDAC6HDAC4 | |
| SCHEMBL9089458 | 0.72 | NR1I2 (0.67) | NR1I2CYP3A4CYP2D6HDAC6HDAC4 | |
| SCHEMBL8663042 | 0.71 | NR1I2 (0.46) | NR1I2CYP3A4CYP2D6HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |