Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555395 | 0.90 | L3MBTL1 (0.36) | L3MBTL1S1PR1S1PR3LMNARAB9A | |
| SCHEMBL8552168 | 0.86 | HDAC4 (0.37) | S1PR1S1PR3RAB9ANR1I2CYP3A4 | |
| SCHEMBL8552757 | 0.86 | NR1I2 (0.50) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8551731 | 0.77 | SMN1; SMN2 (0.31) | RAB9ANFKB1NFKB2RELANPC1 | |
| SCHEMBL8687267 | 0.77 | L3MBTL1 (0.37) | L3MBTL1S1PR1S1PR3LMNARAB9A | |
| SCHEMBL8554371 | 0.76 | NR1I2 (0.49) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8553627 | 0.76 | HDAC4 (0.35) | S1PR1S1PR3NR1I2CYP3A4CYP2D6 | |
| SCHEMBL9087864 | 0.68 | NR1I2 (0.47) | L3MBTL1S1PR1S1PR3LMNATSHR | |
| SCHEMBL6982022 | 0.67 | NR1I2 (0.47) | L3MBTL1S1PR1S1PR3NR1I2CYP3A4 | |
| SCHEMBL6974407 | 0.67 | NR1I2 (0.47) | L3MBTL1S1PR1S1PR3NR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |