Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552905 | 0.90 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL8644651 | 0.87 | ITGB3 (0.41) | HRH3ITGB3ITGA2BHTR7 | |
| SCHEMBL8593632 | 0.85 | HTR2B (0.45) | HRH3ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8552786 | 0.85 | HTR2B (0.45) | HRH3ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8553302 | 0.82 | HRH3 (0.41) | HRH3ITGB3ITGA2B | |
| SCHEMBL8595580 | 0.79 | HTR7 (0.34) | HRH3HTR7DRD4SLC6A4 | |
| SCHEMBL8554007 | 0.79 | HRH3 (0.42) | HRH3ITGB3ITGA2BHTR7DRD4 | |
| SCHEMBL8356623 | 0.77 | ITGB3 (0.38) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8550693 | 0.75 | HTR2B (0.43) | HRH3ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8552884 | 0.74 | HTR2B (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |