Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623696 | 0.89 | HTR2B (0.38) | HTR2BCCR8TDP1L3MBTL1HRH3 | |
| SCHEMBL8355541 | 0.88 | HTR2B (0.45) | HTR2BCCR8TDP1L3MBTL1HRH3 | |
| SCHEMBL8552786 | 0.87 | HTR2B (0.45) | HTR2BCCR8HRH3POLB | |
| SCHEMBL8593632 | 0.87 | HTR2B (0.45) | HTR2BCCR8HRH3POLB | |
| SCHEMBL8351626 | 0.83 | ALDH1A1 (0.43) | HTR2BHRH3KMT2A | |
| SCHEMBL8551353 | 0.82 | HTR2B (0.42) | HTR2BCCR8HRH3 | |
| SCHEMBL8550693 | 0.79 | HTR2B (0.43) | HTR2BCCR8HRH3 | |
| SCHEMBL8590784 | 0.76 | HRH3 (0.40) | HTR2BHRH3 | |
| SCHEMBL8551028 | 0.74 | HTR2B (0.41) | HTR2B | |
| SCHEMBL8549444 | 0.74 | OGA (0.45) | HTR2BCCR8HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |