Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.87 |
| ▸ | DRD4 | P21917 | 1/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907364 | 0.93 | HTR2A (1.00) | HTR2ADRD4KMT2AMEN1CHRM2 | |
| SCHEMBL7516300 | 0.93 | HTR2A (1.00) | HTR2ADRD4KMT2AMEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL8552262 | 0.92 | HTR2A (0.98) | HTR2ADRD4KMT2AMEN1CHRM2 | |
| Bromide SCHEMBL8553366 | 0.89 | HTR2A (0.91) | HTR2ADRD4KMT2AMEN1CHRM2 | |
| SCHEMBL3726273 | 0.84 | HTR2A (0.79) | HTR2ADRD4KMT2AMEN1CHRM2 | |
| SCHEMBL13041313 | 0.82 | DRD4 (0.75) | HTR2ADRD4KMT2AMEN1CHRM2 | |
| SCHEMBL6350366 | 0.74 | KMT2A (0.62) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL8556407 | 0.73 | DRD4 (0.59) | HTR2ADRD4KMT2AMEN1ALDH1A1 | |
| SCHEMBL8552184 | 0.70 | DRD4 (0.61) | HTR2ADRD4KMT2AMEN1DRD3 | |
| SCHEMBL8558550 | 0.69 | HTR2A (0.59) | HTR2ADRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |