⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138242 | 0.78 | — | — | |
| SCHEMBL546117 | 0.76 | HTT (0.32) | — | |
| SCHEMBL545831 | 0.74 | — | — | |
| SCHEMBL546329 | 0.72 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL3148463 | 0.65 | — | — | |
| SCHEMBL143917 | 0.65 | — | — | |
| SCHEMBL3148368 | 0.65 | — | — | |
| SCHEMBL16497502 | 0.61 | — | — | |
| SCHEMBL442765 | 0.61 | PIM1 (0.30) | — | |
| SCHEMBL438847 | 0.61 | EEF2K (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719265-B1 | NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 1998-12-02 | — | — | EP | claimed |
| US-5721341-A | Derivatives of nucleosides, processes for the production of these derivatives of nucleosides and specific polyclonal and monoclonal antibodies of these derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1998-02-24 | — | — | US | claimed |