⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042013 | 0.74 | — | — | |
| SCHEMBL143917 | 0.70 | — | — | |
| SCHEMBL3148368 | 0.70 | — | — | |
| SCHEMBL440393 | 0.70 | — | — | |
| SCHEMBL8884963 | 0.67 | — | — | |
| SCHEMBL3357201 | 0.67 | — | — | |
| SCHEMBL3357209 | 0.67 | — | — | |
| SCHEMBL8554982 | 0.67 | — | — | |
| SCHEMBL545786 | 0.65 | HKDC1 (0.33) | — | |
| SCHEMBL8552885 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284832-B1 | APTAMER WITH IMPROVED RATE OF DISSOCIATION, AND NON-COVALENT APTAMER-TARGET COMPLEX THEREOF | SOMALOGIC OPERATING CO INC (US) | 2023-06-07 | — | — | EP | claimed |
| US-11597745-B2 | β-modified phosphoric acid compound precursor, β-modified phosphoric acid compound, reaction inhibitor and medicine containing the same, and method for inhibiting reaction | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2023-03-07 | — | — | US | claimed |
| EP-3284832-A2 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | Somalogic, Inc. (US) | 2018-02-21 | — | — | EP | claimed |
| EP-2933340-B1 | Aptamers with uridines and/or thymidines substituted at the 5-position with a benzyl group | SOMALOGIC INC (US) | 2017-09-06 | — | — | EP | claimed |
| US-20170137819-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. | 2017-05-18 | — | — | US | claimed |
| EP-2933340-A1 | Chemically modified aptamers with improved off-rates | Somalogic, Inc. (US) | 2015-10-21 | — | — | EP | claimed |
| US-20150197753-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. | 2015-07-16 | — | — | US | claimed |
| US-8975388-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2015-03-10 | — | — | US | claimed |
| US-8404830-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2013-03-26 | — | — | US | claimed |
| US-8076310-B2 | Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-12-13 | — | — | US | claimed |
| US-20080139566-A1 | SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF | HOWELL AMY R | 2008-06-12 | — | — | US | claimed |
| JP-2007512358-A | — | — | 2007-05-17 | — | — | JP | claimed |
| EP-1685127-A1 | HETEROCYCLYL-SUBSTITUTED OXETANES FOR THE TREATMENT OF PROLIFERATIVE OR INFECTIOUS DISEASES | The University of Connecticut (US) | 2006-08-02 | — | — | EP | claimed |
| US-20050215568-A1 | Substituted oxetanes, method of making, and method of use thereof | UNIVERSITY OF CONNECTICUT, THE | 2005-09-29 | — | — | US | claimed |
| WO-2005051944-A1 | HETEROCYCLYL-SUBSTITUTED OXETANES FOR THE TREATMENT OF PROLIFERATIVE OR INFECTIOUS DISEASES | UNIVERSITY OF CONNECTICUT (US) | 2005-06-09 | — | — | WO | claimed |
| JP-3047045-B2 | — | — | 2000-05-29 | — | — | JP | claimed |
| US-6034087-A | VIRICIDE AGAINST HEPATITIS B | CHONG KUN DANG CORP. (KR) | 2000-03-07 | — | — | US | claimed |
| US-6015886-A | ANTISENSE AGENTS WITH MODIFICATIONS INCLUDING P-ALKOXY AND 2'-O-METHYL GROUPS; NUCLEASE RESISTANT, ABILITY TO ACTIVATE BACTERIAL RIBONUCLEASE H, FORM STABLE DUPLEXES WITH RNA, AND HAVE STRONG HYDROPHOBICITY FOR EFFICIENT CELLULAR UPTAKE | CHEMGENES CORPORATION (US) | 2000-01-18 | — | — | US | claimed |
| EP-0869953-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP (KR) | 1998-10-14 | — | — | EP | claimed |
| WO-1996012716-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP. (KR) | 1996-05-02 | — | — | WO | claimed |