Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557412 | 0.99 | ALOX5 (0.44) | ALOX5ALOX5APCYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL8557396 | 0.99 | ALOX5 (0.44) | ALOX5ALOX5APCYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL8552934 | 0.98 | ALOX5 (0.44) | ALOX5ALOX5APCYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL8554759 | 0.86 | CYSLTR2 (0.44) | ALOX5ALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL8554770 | 0.86 | CYSLTR2 (0.44) | ALOX5ALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL8555687 | 0.86 | GPBAR1 (0.60) | ALOX5CYSLTR1GPBAR1CYSLTR2HDAC6 | |
| SCHEMBL8555246 | 0.85 | GPBAR1 (0.61) | ALOX5CYSLTR1GPBAR1CYSLTR2HDAC6 | |
| SCHEMBL8554925 | 0.85 | GPBAR1 (0.61) | ALOX5CYSLTR1GPBAR1CYSLTR2HDAC6 | |
| SCHEMBL8555104 | 0.84 | GPBAR1 (0.60) | ALOX5CYSLTR1GPBAR1CYSLTR2HDAC6 | |
| SCHEMBL8557903 | 0.81 | ALOX5 (0.56) | ALOX5ALOX5APCYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |