Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | C1R | P00736 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191018 | 0.81 | HTR6 (0.42) | HTR6HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL8552954 | 0.78 | POLB (0.41) | HTR6THRATHRB | |
| SCHEMBL3698727 | 0.64 | CA9 (0.47) | HTR6C1RPRSS1HTR1AHTR2A | |
| SCHEMBL3703471 | 0.63 | CA1 (0.53) | HTR6C1RPRSS1HTR1AHTR2A | |
| SCHEMBL3698233 | 0.62 | CA1 (0.45) | HTR6C1RPRSS1HTR1AHTR2A | |
| SCHEMBL13979927 | 0.60 | HTT (0.64) | HTR2AHTR2CCYP2C19 | |
| SCHEMBL14415470 | 0.58 | HTR2A (0.51) | HTR6C1RPRSS1HTR2AHTR2C | |
| SCHEMBL14415467 | 0.58 | HTT (0.54) | C1RPRSS1HTR2AHTR2CHTR7 | |
| SCHEMBL878485 | 0.57 | CA1 (0.61) | HTR6PRSS1HTR2AHTR2CCYP2C19 | |
| SCHEMBL15851886 | 0.56 | AHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |