Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191015 | 0.83 | HTR1F (0.51) | POLBMAPTHTR1FHTR6BCHE | |
| SCHEMBL8552957 | 0.78 | HTR6 (0.36) | HTR6THRATHRB | |
| SCHEMBL8548601 | 0.70 | HTR1F (0.45) | HTR1F | |
| SCHEMBL8551588 | 0.70 | TMEM97 (0.48) | MAPTHTR1FTP53SMN1; SMN2 | |
| SCHEMBL8552580 | 0.68 | HTR1F (0.65) | POLBMAPTHTR1FHTR6TP53 | |
| Hydrochloric Acid SCHEMBL8552084 | 0.67 | MAPT (0.40) | POLBMAPTHTR1FSMN1; SMN2THRB | |
| SCHEMBL8548549 | 0.66 | HTR1F (0.50) | POLBMAPTHTR1FTP53SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL8552469 | 0.64 | TMEM97 (0.42) | MAPTTP53RXFP1 | |
| SCHEMBL8548442 | 0.64 | HTR1F (0.48) | MAPTHTR1FTP53SMN1; SMN2KMT2A | |
| SCHEMBL6240037 | 0.63 | FGF1 (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |