Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552968 | 1.00 | HTR2A (0.49) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL8556127 | 0.78 | TAAR1 (0.43) | TAAR1IDO1MIFMAOBMAOA | |
| SCHEMBL8556130 | 0.78 | TAAR1 (0.43) | TAAR1IDO1MIFMAOBMAOA | |
| SCHEMBL6264578 | 0.78 | HTR2A (0.56) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL28569050 | 0.77 | FBP1 (0.53) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL5703037 | 0.75 | IDO1 (0.59) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL39835 | 0.75 | TAAR1 (0.56) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL14894202 | 0.75 | FBP1 (0.57) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL8403636 | 0.75 | HTR2A (0.53) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL10263844 | 0.75 | IDO1 (0.59) | HTR2AHTR2BHTR2CTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626951-B1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BRITISH TECH GROUP (GB) | 1998-07-29 | — | — | EP | disclosed |
| US-5578626-A | Pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-11-26 | — | — | US | disclosed |
| US-5476867-A | Pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-12-19 | — | — | US | disclosed |
| EP-0626951-A1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BTG INTERNATIONAL LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993017004-A1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-09-02 | — | — | WO | disclosed |