Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556127 | 1.00 | TAAR1 (0.43) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL8552966 | 0.78 | HTR2A (0.49) | TAAR1IDO1NPC1RAB9AMAOB | |
| SCHEMBL8552968 | 0.78 | HTR2A (0.49) | TAAR1IDO1NPC1RAB9AMAOB | |
| SCHEMBL8552112 | 0.77 | MAOB (0.48) | IDO1NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL8552111 | 0.77 | MAOB (0.48) | IDO1NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL10650457 | 0.76 | TAAR1 (0.49) | TAAR1IDO1AGXTMAOBFBP1 | |
| SCHEMBL6263775 | 0.75 | TAAR1 (0.50) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL167999 | 0.72 | TAAR1 (0.52) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL16167413 | 0.72 | IDO1 (0.55) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL26033709 | 0.72 | IDO1 (0.55) | TAAR1IDO1AGXTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626951-B1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BRITISH TECH GROUP (GB) | 1998-07-29 | — | — | EP | disclosed |
| US-5578626-A | Pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-11-26 | — | — | US | disclosed |
| US-5476867-A | Pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-12-19 | — | — | US | disclosed |
| EP-0626951-A1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BTG INTERNATIONAL LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993017004-A1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-09-02 | — | — | WO | disclosed |