Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CRHBP | P24387 | 3/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553002 | 1.00 | MAPK1 (0.51) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8548616 | 0.99 | MAPK1 (0.50) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8548615 | 0.99 | MAPK1 (0.50) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL14505847 | 0.86 | MAPK1 (0.56) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18820626 | 0.86 | MAPK1 (0.56) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL17470433 | 0.78 | MAPK1 (0.57) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8553005 | 0.75 | ALDH1A1 (0.53) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8552995 | 0.75 | ALDH1A1 (0.53) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10029682 | 0.74 | MAPK1 (0.56) | MAPK1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2334505 | 0.74 | RECQL (0.59) | MAPK1HTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |