SCHEMBL8553004

SCHEMBL8553004

c1nncc2cc3c(cc12)OCO3

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
CASP3 P42574 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
CYP3A4 P08684 2/20 0.41
LMNA P02545 2/20 0.40
TP53 P04637 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.38
RPS6KB2 Q9UBS0 1/20 0.37
CA2 P00918 1/20 0.37
HSD17B10 Q99714 2/20 0.37
PDGFRB P09619 1/20 0.37
PDGFRA P16234 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9923670 0.79
SCHEMBL8930679 0.75 ABCG2 (0.53) L3MBTL1CYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL30466406 0.74 GAA (0.46) L3MBTL1CASP3SENP7SENP8SENP6
SCHEMBL1201537 0.74 GAA (0.46) L3MBTL1CASP3SENP7SENP8SENP6
SCHEMBL8554879 0.73 ALDH1A1 (0.42) CYP3A4LMNATP53SMN1; SMN2NPC1
SCHEMBL1840582 0.72 ABCG2 (0.60) L3MBTL1CYP3A4LMNATP53SMN1; SMN2
SCHEMBL13519624 0.72 L3MBTL1 (0.50) L3MBTL1CASP3SENP7SENP8SENP6
SCHEMBL1201565 0.72 L3MBTL1 (0.39) L3MBTL1CASP3SENP7SENP8SENP6
SCHEMBL22045619 0.71 ALDH1A1 (0.53) ALDH1A1MAPTHPGD
SCHEMBL23625930 0.70 L3MBTL1 (0.40) L3MBTL1CASP3SENP7SENP8SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 US disclosed
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 US disclosed
EP-0859763-A1 DIHYDROPHTHALAZINE ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS Bearsden Bio, Inc. (US) 1998-08-26 EP disclosed