Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091116 | 0.80 | TSHR (0.43) | TSHRHPGDHSD17B10L3MBTL1MAPT | |
| SCHEMBL8551826 | 0.77 | FFAR4 (0.44) | TSHRMEN1KMT2ATP53MAPK1 | |
| SCHEMBL8553780 | 0.73 | NPC1 (0.36) | TSHRMEN1KMT2ANPC1LMNA | |
| SCHEMBL8553886 | 0.72 | PPARG (0.35) | TSHRHPGDHSD17B10NPSR1MEN1 | |
| SCHEMBL9089935 | 0.70 | HDAC6 (0.39) | HPGDTP53KIFC1 | |
| SCHEMBL8866848 | 0.70 | ALOX15 (0.46) | HPGDMEN1KMT2ANPC1LMNA | |
| SCHEMBL8603712 | 0.69 | NR1I2 (0.37) | TSHRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8553777 | 0.69 | SMN1; SMN2 (0.33) | HPGDHSD17B10NPC1RAB9AMAPK1 | |
| SCHEMBL8661861 | 0.69 | SMN1; SMN2 (0.32) | HPGDHSD17B10NPC1RAB9AMAPK1 | |
| SCHEMBL16837506 | 0.68 | DGKA (0.46) | TSHRKMT2AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |