Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604571 | 0.88 | PPARG (0.35) | PPARGPPARASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8553777 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8661861 | 0.78 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8553053 | 0.72 | TSHR (0.36) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL8551826 | 0.71 | FFAR4 (0.44) | ALDH1A1KDM4EMAPK1FFAR1TSHR | |
| SCHEMBL8553807 | 0.70 | CTSA (0.35) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8551725 | 0.70 | — | — | |
| SCHEMBL9091116 | 0.69 | TSHR (0.43) | HPGDHSD17B10MAPK1TSHRTP53 | |
| SCHEMBL8556589 | 0.68 | RAB9A (0.35) | PPARASMN1; SMN2FFAR1NPC1RAB9A | |
| SCHEMBL8824429 | 0.68 | THRA (0.39) | ALDH1A1MAPK1KIFC1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |