Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13860340 | 0.85 | GAA (0.57) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL6205595 | 0.83 | HTT (0.46) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL2546236 | 0.81 | GAA (0.68) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL11546523 | 0.79 | GAA (0.65) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL1179221 | 0.78 | GABRP (0.43) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL13858699 | 0.78 | TDP1 (0.52) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL3994806 | 0.76 | GAA (0.61) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL3615656 | 0.76 | GAA (0.61) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL13860443 | 0.76 | GAA (1.00) | GAAMAPTLMNAALDH1A1HPGD | |
| SCHEMBL574674 | 0.76 | GAA (0.65) | GAAMAPTLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |