Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653955 | 0.83 | F2 (0.37) | ALDH1A1LMNAMAPTKMT2AHPGD | |
| SCHEMBL20792234 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKMT2AHPGD | |
| SCHEMBL7466472 | 0.81 | KIF11 (0.47) | ALDH1A1MAPTCA1CA2ACHE | |
| SCHEMBL6926741 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTKMT2AHPGD | |
| SCHEMBL22302 | 0.78 | F2 (0.52) | ALDH1A1LMNAKMT2AHPGDMEN1 | |
| SCHEMBL25513159 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTKMT2AHPGD | |
| SCHEMBL28209363 | 0.74 | F2 (0.48) | ALDH1A1LMNAKMT2AHPGDMEN1 | |
| SCHEMBL1125078 | 0.74 | F2 (0.52) | ALDH1A1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL1124662 | 0.74 | F2 (0.52) | ALDH1A1KMT2AMEN1CA1CA2 | |
| SCHEMBL5655146 | 0.74 | F2 (0.52) | ALDH1A1MAPTTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |