Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183802 | 0.72 | ALOX5 (0.44) | GAAMAPTL3MBTL1KDM4EHTT | |
| SCHEMBL6154136 | 0.70 | PARP1 (0.46) | MEN1KMT2AF2PLGELANE | |
| SCHEMBL11136048 | 0.67 | GAA (1.00) | GAAGSK3AGSK3BKMT2AF2 | |
| SCHEMBL7473989 | 0.67 | GAA (0.50) | GAAGSK3AGSK3BMGLLMEN1 | |
| SCHEMBL4369976 | 0.64 | GAA (0.60) | GAAGSK3AGSK3BMGLLMEN1 | |
| SCHEMBL29607448 | 0.63 | GAA (0.78) | GAAGSK3AGSK3BMEN1KMT2A | |
| SCHEMBL9445305 | 0.63 | GAA (0.50) | GAAGSK3AGSK3BMEN1KMT2A | |
| SCHEMBL8489655 | 0.63 | GAA (0.50) | GAAGSK3AGSK3BMEN1KMT2A | |
| SCHEMBL8556304 | 0.62 | ALOX5 (0.54) | GAAMGLLMEN1KMT2ASIGMAR1 | |
| SCHEMBL2438031 | 0.62 | SIGMAR1 (0.60) | GAAGSK3AGSK3BMGLLF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756598-B1 | SUBSTITUTED 5,6-DIHYDRO-5-OXO-1,4-DITHIINO-(2,3-D)-PYRIDAZINE-2,3-DICARBONITRILES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIALS | DOW CHEMICAL CO (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5488051-A | BACTERICIDES, FUNGICIDES, ALGICIDES AND ANTIPROTOZOA AGENTS | THE DOW CHEMICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |