Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 4/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860653 | 0.80 | GAA (0.53) | GAAGSK3AGSK3BF2PLG | |
| SCHEMBL2438031 | 0.74 | SIGMAR1 (0.60) | GAAGSK3AGSK3BF2PLG | |
| SCHEMBL27538197 | 0.69 | SMN1; SMN2 (0.50) | GAASIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5075479 | 0.67 | SIGMAR1 (0.56) | GAAGSK3AGSK3BF2PLG | |
| SCHEMBL9193147 | 0.67 | ALOX5 (0.46) | GAAGSK3AGSK3BMEN1KMT2A | |
| SCHEMBL8553203 | 0.67 | GAA (0.50) | GAAGSK3AGSK3BF2PLG | |
| SCHEMBL11136048 | 0.67 | GAA (1.00) | GAAGSK3AGSK3BF2PLG | |
| SCHEMBL6734920 | 0.67 | GSK3A (0.47) | GAAGSK3AGSK3BF2PLG | |
| SCHEMBL1488276 | 0.66 | L3MBTL1 (0.56) | GSK3AGSK3BF2PLGELANE | |
| SCHEMBL11085801 | 0.66 | DDB1 (0.51) | GAAGSK3AGSK3BF2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005471-B1 | PYRAZOLO(3,4-D)PYRIMIDINES WITH ANTICONVULSIVE AND ANTIALLERGIC/ANTIASTHMATIC ACTION | DRESDEN ARZNEIMITTEL (DE) | 2002-09-04 | — | — | EP | disclosed |