Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397807 | 0.82 | SMN1; SMN2 (0.35) | ARFASNSMN1; SMN2GABRPGABRD | |
| SCHEMBL8401038 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2GABRPGABRDNR1I2LMNA | |
| SCHEMBL8398602 | 0.80 | SMN1; SMN2 (0.37) | ARSMN1; SMN2GABRPGABRDNR1I2 | |
| SCHEMBL8556302 | 0.79 | KMT2A (0.34) | SMN1; SMN2GABRPGABRDNR1I2LMNA | |
| SCHEMBL8554269 | 0.78 | GABRP (0.34) | SMN1; SMN2GABRPGABRDNR1I2LMNA | |
| SCHEMBL8554009 | 0.78 | GABRP (0.34) | SMN1; SMN2GABRPGABRDNR1I2LMNA | |
| SCHEMBL7970750 | 0.77 | GABRP (0.33) | SMN1; SMN2GABRPGABRDNR1I2LMNA | |
| SCHEMBL8554142 | 0.76 | SHMT1 (0.32) | ARSMN1; SMN2GABRPGABRDNR1I2 | |
| SCHEMBL8401036 | 0.75 | GABRP (0.37) | SMN1; SMN2GABRPGABRDNR1I2LMNA | |
| SCHEMBL8554505 | 0.73 | GABRP (0.36) | SMN1; SMN2GABRPGABRDNR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918756-A1 | PARASITICIDAL PYRAZOLES | Pfizer Limited (GB) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004530-A1 | PARASITICIDAL PYRAZOLES | PFIZER LIMITED (GB) | 1998-02-05 | — | — | WO | disclosed |