Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 7/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872856 | 0.78 | ALDH1A1 (0.43) | ESR1ESR2MAOAALDH1A1NQO1 | |
| SCHEMBL6354852 | 0.71 | MAOA (0.63) | MAOAALDH1A1NQO1SMN1; SMN2KDM5A | |
| SCHEMBL10756036 | 0.69 | CYP3A4 (0.41) | ESR1ESR2MAOAEGFRALDH1A1 | |
| SCHEMBL3383138 | 0.69 | MAOA (0.64) | MAOAEGFRALDH1A1NQO1SMN1; SMN2 | |
| SCHEMBL19142155 | 0.67 | CD44 (0.48) | ESR1ESR2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL3884406 | 0.67 | MAOA (0.48) | ESR1ESR2MAOAEGFRALDH1A1 | |
| SCHEMBL6650775 | 0.67 | ALDH1A1 (0.53) | ALDH1A1NQO1SMN1; SMN2POLBKDM4E | |
| SCHEMBL28390041 | 0.67 | POLB (0.43) | ESR1ESR2ALDH1A1NQO1SMN1; SMN2 | |
| SCHEMBL31472745 | 0.66 | CA1 (0.66) | ESR1ESR2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8629831 | 0.66 | KDM4E (0.54) | ESR1ESR2MAOAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685474-B1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1998-09-16 | — | — | EP | claimed |
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |
| EP-0685474-A1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | claimed |
| EP-0685474-B1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1998-09-16 | — | — | EP | disclosed |
| EP-0685474-B1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1998-09-16 | — | — | EP | disclosed |
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| CN-1119187-A | oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1996-03-27 | — | — | CN | disclosed |
| CN-1119187-A | oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1996-03-27 | — | — | CN | disclosed |
| EP-0685474-A1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0685474-A1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0685474-A1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |