Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180418 | 0.85 | HTR1F (0.43) | SMN1; SMN2TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL8553305 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL6672030 | 0.74 | HTR1F (0.46) | SMN1; SMN2TSHRMAPK1RAB9ANPC1 | |
| SCHEMBL8548267 | 0.66 | KDM4E (0.41) | SMN1; SMN2ALDH1A1KDM4EGAAHTT | |
| SCHEMBL7143778 | 0.65 | HTR1F (0.61) | RAB9AALDH1A1KDM4EITKNPSR1 | |
| SCHEMBL8191020 | 0.64 | HTR1F (0.42) | SMN1; SMN2MAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL7146077 | 0.64 | HTR1F (0.62) | SMN1; SMN2RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL8546895 | 0.62 | MEN1 (0.43) | SMN1; SMN2MAPK1RAB9ANPC1ALDH1A1 | |
| SCHEMBL8180841 | 0.62 | HTR1F (0.44) | SMN1; SMN2MAPK1ALDH1A1GAAITK | |
| SCHEMBL7138281 | 0.62 | HTR1F (0.62) | SMN1; SMN2ALDH1A1KDM4EGAAITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |