Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672030 | 0.85 | HTR1F (0.46) | SMN1; SMN2ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL8553336 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL8180418 | 0.84 | HTR1F (0.43) | SMN1; SMN2ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL8550329 | 0.79 | KDM4E (0.40) | SMN1; SMN2ALDH1A1KDM4EGAAGBA1 | |
| SCHEMBL8550531 | 0.79 | EGFR (0.42) | SMN1; SMN2ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL8546895 | 0.78 | MEN1 (0.43) | SMN1; SMN2ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL8551309 | 0.78 | RAB9A (0.48) | SMN1; SMN2ALDH1A1KDM4EGAARAB9A | |
| Acetic Acid SCHEMBL8548884 | 0.78 | JAK2 (0.39) | SMN1; SMN2ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL8552082 | 0.74 | KDM4E (0.45) | SMN1; SMN2ALDH1A1KDM4EGAA | |
| Hexanoate SCHEMBL8547899 | 0.73 | GBA1 (0.36) | SMN1; SMN2ALDH1A1KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |