Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801271 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPK1L3MBTL1TDP1LMNA | |
| SCHEMBL3174502 | 0.82 | CYP4F2 (0.65) | ALDH1A1TDP1CYP4F2CYP4A11LMNA | |
| SCHEMBL28662041 | 0.80 | TDP1 (0.54) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL304176 | 0.79 | TDP1 (0.78) | ALDH1A1MAPK1L3MBTL1TDP1LMNA | |
| SCHEMBL24405114 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL306178 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL24405103 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL27957232 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP4F2 | |
| SCHEMBL6517024 | 0.78 | TSHR (0.46) | ALDH1A1TDP1CYP4F2CYP4A11LMNA | |
| SCHEMBL2563233 | 0.77 | KEAP1 (0.50) | MAPK1TDP1LMNASLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854863-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997003951-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |