Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951904 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL12488440 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL2090659 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8188473 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2NPSR1APP | |
| SCHEMBL2093741 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL8472083 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HPGDSMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8202114 | 0.76 | ALDH1A1 (0.96) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL19626767 | 0.75 | KIF11 (0.40) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8188518 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL15423314 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |