Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 3/20 | 0.42 |
| ▸ | EDNRA | P25101 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556764 | 0.92 | MAPT (0.54) | MAPTALDH1A1LIMK2LMNAMEN1 | |
| SCHEMBL8560356 | 0.90 | ALDH1A1 (0.51) | MAPTALDH1A1LIMK2LMNAHPGD | |
| SCHEMBL8557761 | 0.88 | MAPT (0.49) | MAPTALDH1A1LIMK2LMNAMEN1 | |
| SCHEMBL8555221 | 0.88 | MAPT (0.56) | MAPTALDH1A1LIMK2LMNAMEN1 | |
| SCHEMBL8555498 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8553397 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1LIMK2LMNAKMT2A | |
| SCHEMBL8561399 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1LIMK2LMNAHPGD | |
| SCHEMBL8556990 | 0.85 | MAPT (0.47) | MAPTALDH1A1LIMK2LMNAKMT2A | |
| SCHEMBL8557213 | 0.85 | MAPT (0.47) | MAPTALDH1A1LIMK2LMNAHPGD | |
| SCHEMBL8558062 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1LIMK2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |