Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109679 | 0.85 | ALOX5 (0.37) | ALOX5TRPV1 | |
| SCHEMBL2107548 | 0.83 | ALOX5 (0.43) | ALOX5TRPV1 | |
| SCHEMBL8554702 | 0.81 | MAP2K1 (0.32) | ALOX5 | |
| SCHEMBL8557003 | 0.81 | TRPV1 (0.30) | TRPV1 | |
| SCHEMBL2108067 | 0.79 | CREBBP (0.36) | ALOX5 | |
| SCHEMBL8979547 | 0.78 | ALOX5 (0.33) | ALOX5TRPV1 | |
| SCHEMBL8557425 | 0.78 | ALOX5 (0.34) | ALOX5TRPV1 | |
| SCHEMBL8557662 | 0.76 | ALOX5 (0.47) | ALOX5TRPV1 | |
| SCHEMBL2108288 | 0.75 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL8557701 | 0.75 | ALOX5 (0.32) | ALOX5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623614-B1 | 4-Aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5478842-A | Antiinflammatory agents, antiallergens, drugs for treatment of diseases mediated by leukotrienes | ZENECA LIMITED (GB) | 1995-12-26 | — | — | US | disclosed |
| WO-1994025453-A1 | 4-ARYL-4-HYDROXY-TETRAHYDROPYRANS AND 3-ARYL-3-HYDROXY-TETRAHYDROFURANS AS 5-LIPOXYGENASE INHIBITORS | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |
| EP-0623614-A1 | 4-Aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |