Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557701 | 0.90 | ALOX5 (0.32) | MAP2K1ALOX5 | |
| SCHEMBL8557726 | 0.89 | MAP2K1 (0.31) | MAP2K1 | |
| SCHEMBL8553537 | 0.86 | ALOX5 (0.36) | MAP2K1ALOX5 | |
| SCHEMBL8557425 | 0.86 | ALOX5 (0.34) | MAP2K1ALOX5 | |
| SCHEMBL2108288 | 0.85 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL2107548 | 0.84 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL2109679 | 0.84 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL8556671 | 0.81 | MAP2K1 (0.32) | MAP2K1 | |
| SCHEMBL8553417 | 0.81 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL8552161 | 0.79 | MAP2K1 (0.32) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623614-B1 | 4-Aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | claimed |