Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554702 | 0.86 | MAP2K1 (0.32) | ALOX5MAP2K1 | |
| SCHEMBL8555899 | 0.85 | ALOX5 (0.37) | ALOX5TRPV1 | |
| SCHEMBL2109679 | 0.83 | ALOX5 (0.37) | ALOX5TRPV1 | |
| SCHEMBL2108288 | 0.82 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL2107548 | 0.81 | ALOX5 (0.43) | ALOX5TRPV1 | |
| SCHEMBL8557701 | 0.80 | ALOX5 (0.32) | ALOX5TRPV1MAP2K1 | |
| SCHEMBL8554174 | 0.78 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL8553417 | 0.78 | ALOX5 (0.33) | ALOX5TRPV1 | |
| SCHEMBL8557726 | 0.77 | MAP2K1 (0.31) | MAP2K1 | |
| SCHEMBL2108067 | 0.75 | CREBBP (0.36) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623614-B1 | 4-Aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | claimed |